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Instructions to Contributors


Manuscripts containing original material are accepted for consideration if the article has not been published elsewhere. Abstracts or press reports published in connection with scientific meetings are exempt from this restriction. Statistical methodology and conformity with concepts of good clinical practice should be meticulously evaluated. Each manuscript should be accompanied with the following information:

A cover letter signed by all authors certifying that the work has not been published previously or submitted elsewhere for review must be included with all submissions. The manuscript should be double-spaced, written in 12-point type with consecutively numbered pages. The manuscript must contain one original set of figures and tabular data. Seperately to the letter a copy of the manuscript in electronic format (ASCII) should be sent by email to (Please revmove - before and after @)Each submission packet should be mailed to the editorial office at the following address: Helmut Eckardt, Klinik und Forschung, Waldstr. 57, D-15566 Schöneiche bei Berlin. Please supply a word count (not including abstract or references).

Length of manuscripts

Length of abstract

Letter 250-500

words n.a.


500-1000 words (only upon invitation) 150

Case report

800-1600 words 150


900-1100 words (only upon invitation) n.a.

Clinical Study

1600-3000 words 250

Laboratory Study

1600 -3000 words 250


3000-6000 words (only upon invitation) 250

Title page

A title page containing the corresponding author's complete mailing address, telephone and fax numbers, and e-mail address (if available) should be included, as well as the complete names and affiliations of all co-authors with their respective highest academic degree(s) and institutional affiliation.

Key words

A list of key words (minimum of two/maximum of six words) should be included on the title page as well. Any sources of support should be listed and must include the name(s) of the grantor(s), applicable grant numbers, and the name of the author who received the funding.


The manuscript must contain an abstract of 150 (250) words or less, if the manuscript is longer than 1500 (2500) words. Abstracts for clinical and laboratory studies should be formatted to outline the object of the study, the methods used to achieve the study goals, and the conclusions drawn from the work. Abstracts for Case reports, Technical notes, Case illustrations, and Historical vignettes should begin with a simple and clear statement of the paper's purpose and be followed by appropriate details that support the authors' conclusions.


References must be double-spaced. List references in consecutive numerical order (not alphabetically). All subsequent reference citations should be to the original number. Cite all references in the text or tables. The style of references is that of Index Medicus. References to journal articles should include (1) author(s) (list all authors and/or editors up to 6; if more than 6, list first 3 and "et al"), (2) title, (3) journal name (as abbreviated in Index Medicus), (4) year, (5) volume number, and (6) inclusive page numbers, in that order. References to books should include (1) author(s) (list all authors and/or editors up to 6; if more than 6, list first 3 and "et al"), (2) chapter title (if any), (3) editor (if any), (4) title of book, (5) city of publication, (6) publisher, and (7) year. Volume and edition numbers, specific pages, and name of translator should be included when appropriate. Do not let the word processing program generate the reference numbers, using such features as automatic footnotes or endnotes.


Include double-spaced legends (maximum length, 40 words) on separate pages. Indicate magnification and stain used for photomicrographs and method of enhancement for digitally enhanced images.

Acknowledgment of receipt

We will acknowledge receipt of your letter by email and we will notify you when we have made a decision about publication. Prepublication proofs will be provided by email in PDF-Format. Authors are responsible for proofreading


Each manuscript (with the exclusion of editorials and comments or other solicit invited papers) is assigned to an editor with expertise in the field discussed, who, in turn, sends it to a minimum of two reviewers. Reviewers give evaluations, suggest improvements, and recommend acceptance or rejection of the paper. Reviewing should be completed within three months. If reviewers disagree, the paper may be sent to a third reviewer. The editor sends a decision letter and the critiques of reviewers to the corresponding author, and the editorial office prepares a detailed list of items to be amended or improved. Authors not following Klinik und Forschung style and format will experience a delay in publication.

Return revised manuscripts to the editor at the address listed in the decision letter stating your disposition of each of the reviewers’ suggestions, item by item. Indicate the page and line number of the revised text and highlight the sections that have been changed on the copy of the revised manuscript to aid the editor in checking revisions. If you wish to reject all or specific suggestions, state your reasons. Manuscripts not received within two months of the date of provisional acceptance will be considered new submissions. Contact the reviewing editor if an extension is needed.


All contributions must be in English.

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